Susceptibility of SARS-CoV-2 to UV irradiation

Susceptibility of SARS-CoV-2 to UV irradiation

Christiane Silke Heilingloh, Ulrich Wilhelm Aufderhorst, Leonie Schipper, Ulf Dittmer, Oliver Witzke, Dongliang Yang, Xin Zheng, Kathrin Sutter, Mirko Trilling, Mira Alt, Eike Steinmann, Adalbert Krawczyk,
Susceptibility of SARS-CoV-2 to UV irradiation,
American Journal of Infection Control,
Volume 48, Issue 10,
2020,
Pages 1273-1275,
ISSN 0196-6553,
https://doi.org/10.1016/j.ajic.2020.07.031.
(https://www.sciencedirect.com/science/article/pii/S0196655320307562)

Abstract: The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 106 TCID50/mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm2. UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.

Keywords: COVID-19; Ultraviolet light; Inactivation

Highlights:

  • SARS-CoV-2 is highly susceptible to irradiation with ultraviolet light.
  • High viral loads of 5 * 106 TCID50/ml SARS-CoV-2 can be inactivated in 9 minutes by UVC irradiation.
  • UVC irradiation represents a suitable disinfection method for SARS-CoV-2.

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